%0 Electronic Article %A Fischer, Thea Kølsen and Aaby, Peter and Mølbak, Kåre and Rodrigues, Amabélia %I University of Chicago Press %D 2010 %D 2010 %G English %@ 0022-1899 %~ Staatliche Kunstsammlungen Dresden, Kunstbibliothek %T Rotavirus Disease in Guinea-Bissau, West Africa: A Review of Longitudinal Community and Hospital Studies %V 202 %J The Journal of Infectious Diseases %V 202 %P S239-S242 %U https://www.jstor.org/stable/25707030 %X

Rotavirus is one of the most common causes of childhood diarrheal disease and deaths in sub-Saharan Africa. This article reviews community- and hospital-based surveillance of rotavirus disease in Bissau, Guinea-Bissau, West Africa. Here, rotavirus infections exhibit a seasonal pattern, with annual epidemics occurring during the relatively dry and cooler months, from January to April, and few cases registered from May to December. Most children (74%) experience their first infection before the age of 2 years, and rotavirus has been identified as the most pathogenic of all diarrheal agents during 2 large prospective studies involving several hundred children <5 years of age. In the hospital setting, rotavirus accounts for a high case-fatality ratio (8%) and a high rate of nosocomial transmission; during the rotavirus season, 23% of all children admitted for nonrotavirus diarrheal disease acquired rotavirus infection during hospitalization (>48 h after admission).

%Z https://katalog.skd.museum/Record/ai-55-aHR0cHM6Ly93d3cuanN0b3Iub3JnL3N0YWJsZS8yNTcwNzAzMA %U https://katalog.skd.museum/Record/ai-55-aHR0cHM6Ly93d3cuanN0b3Iub3JnL3N0YWJsZS8yNTcwNzAzMA