%0 Journal article %A Seed, John R. and Black, Samuel J. %I American Society of Parasitologists %D 1997 %G English %@ 1937-2345 %@ 0022-3395 %~ Staatliche Kunstsammlungen Dresden, Kunstbibliothek %T A Proposed Density-Dependent Model of Long Slender to Short Stumpy Transformation in the African Trypanosomes %V 83 %J The Journal of Parasitology %V 83 %N 4 %P 656-662 %U https://www.jstor.org/stable/3284243 %X

A simple arithmetic model is developed that is based upon the assumptions: (1) that transformation of replicating long slender Trypanosoma brucei to nonreplicating short stumpy forms is parasite population density dependent; (2) that as the slender population increases there is a change in the external environment that triggers the slender to stumpy transformation; and (3) that stumpy forms of T. brucei do not induce the change in external environment that triggers slender to stumpy transformation or do so to a lesser extent than slender forms, thus preventing the proportion of stumpy forms in a population from reaching 100%. A simulation based on these assumptions shared many features with curves on numbers of long slender, intermediate, and short-stumpy forms of T. brucei during the first parasitemic wave of the 3 T. brucei subspecies in intact and immunosuppressed inbred mice.

%Z https://katalog.skd.museum/Record/ai-55-aHR0cHM6Ly93d3cuanN0b3Iub3JnL3N0YWJsZS8zMjg0MjQz %U https://katalog.skd.museum/Record/ai-55-aHR0cHM6Ly93d3cuanN0b3Iub3JnL3N0YWJsZS8zMjg0MjQz